Gonadotropins include FSH, LH, or a combination of both, hCG (human chorionic gonadotropin) may also be used, as it mimics LH in the body. These hormonal medications are typically used when clomiphene citrate fails, or if the pituitary gland can not create LH and FSH on its own.

FSH is employed in vitro fertilization cycles where it stimulates the development of numerous eggs needed for the various Artificial Reproductive Technologies (ART) procedures. It is also used by fertility specialists in stimulated IUI cycles.